Researchers Solve Riddle of Plant Immune System (Botany)

Team led by the University of Göttingen describes influence of molecular mechanisms

How do plants build resilience? An international research team led by the University of Göttingen studied the molecular mechanisms of the plant immune system. They were able to show a connection between a relatively unknown gene and resistance to pathogens. The results of the study were published in the journal The Plant Cell.

Scientists from “PRoTECT” – Plant Responses To Eliminate Critical Threats – investigated the molecular mechanisms of the immune system of a small flowering plant known as thale cress (Arabidopsis thaliana). PRoTECT is an International Research Training Group (IRTG) founded in 2016 with the University of Göttingen and the University of British Columbia in Vancouver. The aim of the study was to identify and describe a specific gene of a particularly disease-resistant plant. The team observed that plants that do not possess this previously little known gene strongly accumulate active acids. In addition, these plants show a significantly increased resistance to pathogens. However, this resistance is accompanied by extremely reduced growth.

The leaf material serves as a basis for metabolite analysis Photo: Philipp William Niemeyer

“We have succeeded in deciphering the molecular connection between the gene product and the inactivation of the acids during normal plant growth,” says Professor Ivo Feußner from the Göttingen Centre for Molecular Biosciences (GZMB). Understanding this interaction provides scientists with a promising approach to improving the natural resistance of crops. “The basic results can be used to help breeders isolate less susceptible plants,” says Lennart Mohnike, first author of the study. “This offers scientists an important way to increase food security and could lead to reduced pesticide use.”

Lennart Mohnike Photo: Philipp William Niemeyer

Featured image: Lennart Mohnike collecting leaf material from bacteria infected plants. Photo: Philipp William Niemeyer


Original publication: Mohnike, et al. The glycosyltransferase UGT76B1 modulates N-hydroxy-pipecolic acid homeostasis and plant immunity. The Plant Cell (2021). Linkhttps://academic.oup.com/plcell/advance-article/doi/10.1093/plcell/koaa045/6080805


Provided by University of Gottingen

Leave a Reply

Fill in your details below or click an icon to log in:

WordPress.com Logo

You are commenting using your WordPress.com account. Log Out /  Change )

Google photo

You are commenting using your Google account. Log Out /  Change )

Twitter picture

You are commenting using your Twitter account. Log Out /  Change )

Facebook photo

You are commenting using your Facebook account. Log Out /  Change )

Connecting to %s