New Findings On How Diabetes Impacts Bone Health (Medicine)

In addition to causing blood sugar imbalances, type 1 diabetes can contribute to nerve damage and sensory abnormalities–a condition call neuropathy–and has been linked to a higher risk of bone fractures. A new study published in the Journal of Bone and Mineral Research has examined the effects of type 1 diabetes and diabetic neuropathy on the skeleton.

Investigators found that type 1 diabetes and diabetic neuropathy have various impacts on bone structure, but these effects do not fully explain the higher fracture risk in patients with type 1 diabetes.

The results suggest that the increase in the risk of fractures in type 1 diabetes is multifactorial, with both skeletal and non-skeletal features involved.

“It is important to investigate what leads to an increased risk of fractures in type 1 diabetes. Our results suggest that in addition to bone features, balance and muscle strength also play a role,” said lead author Tatiane Vilaca, MD, PhD, of the University of Sheffield, in the U.K. “These findings could help improve approaches to fracture prevention.”


Reference: Vilaca, T., Paggiosi, M., Walsh, J.S., Selvarajah, D. and Eastell, R. (2021), The Effects of Type 1 Diabetes and Diabetic Peripheral Neuropathy on the Musculoskeletal System: A Case–Control Study. J Bone Miner Res. https://doi.org/10.1002/jbmr.4271 https://asbmr.onlinelibrary.wiley.com/doi/full/10.1002/jbmr.4271


Provided by Wiley

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