Researchers Identified Factors That Turn Normal Cells Into Liver Cancer Cells (Medicine)

Learning how to make cancer cells from normal cells provides mechanistic understanding about the early developmental stages of human cancer that can be used for preventing these tumorigenic mechanisms in the future. Researchers at the University of Helsinki could show for the first time that normal human fibroblast cells can be converted to specific cancer … Continue reading Researchers Identified Factors That Turn Normal Cells Into Liver Cancer Cells (Medicine)

Solid, Liquid, Or Gas? Technique Quickly Identifies Physical State of Tissues and Tumors (Medicine)

The method could be a route to quicker, less invasive cancer diagnoses. As an organism grows, the feel of it changes too. In the initial stages, an embryo takes on an almost fluid-like state that allows its cells to divide and expand. As it matures, its tissues and organs firm up into their final form. … Continue reading Solid, Liquid, Or Gas? Technique Quickly Identifies Physical State of Tissues and Tumors (Medicine)

Researchers Pinpoint How PARP Inhibitors Combat BRCA1 and BRCA2 Tumor Cells (Medicine)

Key Takeaways PARP inhibitors, used to treat patients with cancer of the breast, ovaries, prostate and pancreas, work by inducing persistent DNA gaps in tumor cells with BRCA1 and BRCA2 mutations. The discovery offers the potential to monitor tumors for the development of resistance to PARP inhibitor therapy, and to identify drug combinations that could … Continue reading Researchers Pinpoint How PARP Inhibitors Combat BRCA1 and BRCA2 Tumor Cells (Medicine)

A Leap in Understanding Hypertrophic Cardiomyopathy (Medicine)

Hypertrophic cardiomyopathy (HCM) is the most common of all genetic heart diseases and is the leading cause of sudden cardiac death. HCM is characterized by an abnormal thickening of the heart muscle, which, over time, can lead to cardiac dysfunction and, ultimately, heart failure.  A paper published June 15 in the Proceedings of the National … Continue reading A Leap in Understanding Hypertrophic Cardiomyopathy (Medicine)

Research Deepens Understanding of Rare Vaccine-Induced blood Clotting Condition (Medicine)

A national study involving UCL has deepened understanding of the symptoms, signs and outcomes of patients with a novel blood-clotting condition associated with the Oxford/AstraZeneca vaccine. The rare condition, known as vaccine-induced immune thrombocytopenia and thrombosis (VITT), is characterised by a blockage of veins and a marked reduction of platelets, which are an important part … Continue reading Research Deepens Understanding of Rare Vaccine-Induced blood Clotting Condition (Medicine)

Potential New Therapeutic Approach For Chronic Inflammatory Bowel Diseases (Medicine)

FAU research team identify messenger substance protecting cells in the intestine Why people suffer from chronic inflammatory bowel diseases (IBD) such as ulcerative colitis is only partially understood. However, it is known that the bacteria of the intestinal flora and dysfunction in the immune system play an important role. In patients with IBD, an increased … Continue reading Potential New Therapeutic Approach For Chronic Inflammatory Bowel Diseases (Medicine)

World Exclusive: CAR-T Cell Therapy Successfully Used Against Autoimmune Disease (Medicine)

20-year-old patient with systemic lupus erythematosus treated with a new therapeutic approach for the first time worldwide It all started with joint pain and a red facial rash: the then 16-year-old Thu-Thao V had already undergone several medical examinations in three cities when she was diagnosed with systemic lupus erythematosus (SLE) in February 2017 at … Continue reading World Exclusive: CAR-T Cell Therapy Successfully Used Against Autoimmune Disease (Medicine)

Adoptive Cell Therapy Plus Checkpoint Inhibitors Show Promise in Non-small cell Lung Cancer (Medicine)

Immunotherapy has become an important tool in the treatment of lung cancer, especially checkpoint inhibitors that block certain immune checkpoints to allow immune cells to recognize and kill cancer cells. Several checkpoint inhibitors targeting PD-1 and PD-L1 have been approved for the treatment of non-small cell lung cancer. However, many patients do not respond well … Continue reading Adoptive Cell Therapy Plus Checkpoint Inhibitors Show Promise in Non-small cell Lung Cancer (Medicine)

Ultrasound Remotely Triggers Immune Cells to Attack Tumors in Mice Without Toxic Side Effects (Medicine)

Bioengineers at the University of California San Diego have developed a cancer immunotherapy that pairs ultrasound with cancer-killing immune cells to destroy malignant tumors while sparing normal tissue. The new experimental therapy significantly slowed down the growth of solid cancerous tumors in mice. The team, led by the labs of UC San Diego bioengineering professor … Continue reading Ultrasound Remotely Triggers Immune Cells to Attack Tumors in Mice Without Toxic Side Effects (Medicine)