The method could be a route to quicker, less invasive cancer diagnoses. As an organism grows, the feel of it changes too. In the initial stages, an embryo takes on an almost fluid-like state that allows its cells to divide and expand. As it matures, its tissues and organs firm up into their final form. … Continue reading Solid, Liquid, Or Gas? Technique Quickly Identifies Physical State of Tissues and Tumors (Medicine) →

Key Takeaways PARP inhibitors, used to treat patients with cancer of the breast, ovaries, prostate and pancreas, work by inducing persistent DNA gaps in tumor cells with BRCA1 and BRCA2 mutations. The discovery offers the potential to monitor tumors for the development of resistance to PARP inhibitor therapy, and to identify drug combinations that could … Continue reading Researchers Pinpoint How PARP Inhibitors Combat BRCA1 and BRCA2 Tumor Cells (Medicine) →

A national study involving UCL has deepened understanding of the symptoms, signs and outcomes of patients with a novel blood-clotting condition associated with the Oxford/AstraZeneca vaccine. The rare condition, known as vaccine-induced immune thrombocytopenia and thrombosis (VITT), is characterised by a blockage of veins and a marked reduction of platelets, which are an important part … Continue reading Research Deepens Understanding of Rare Vaccine-Induced blood Clotting Condition (Medicine) →

Immunotherapy has become an important tool in the treatment of lung cancer, especially checkpoint inhibitors that block certain immune checkpoints to allow immune cells to recognize and kill cancer cells. Several checkpoint inhibitors targeting PD-1 and PD-L1 have been approved for the treatment of non-small cell lung cancer. However, many patients do not respond well … Continue reading Adoptive Cell Therapy Plus Checkpoint Inhibitors Show Promise in Non-small cell Lung Cancer (Medicine) →

Bioengineers at the University of California San Diego have developed a cancer immunotherapy that pairs ultrasound with cancer-killing immune cells to destroy malignant tumors while sparing normal tissue. The new experimental therapy significantly slowed down the growth of solid cancerous tumors in mice. The team, led by the labs of UC San Diego bioengineering professor … Continue reading Ultrasound Remotely Triggers Immune Cells to Attack Tumors in Mice Without Toxic Side Effects (Medicine) →