Medicine Scientists Identify Potential Drug Candidates for Deadly Pediatric Leukemia (Medicine) 15 Apr 2021 Scientists have shown that two existing drug candidates—JAK inhibitors and Mepron—hold potential as treatments for a deadly acute myeloid leukemia (AML) subtype that is more common in children. Scientists at…
Medicine Oncotarget: Hispanic Chronic Myelomonocytic Leukemia Patients (Medicine) 22 Mar 202122 Mar 2021 Oncotarget published "Cytogenetic and molecular landscape and its potential clinical significance in Hispanic CMML patients from Puerto Rico" which reported that one hundred and eleven Hispanic CMML patients from Puerto Rico…
Medicine Study Shows Benefit of Blinatumomab for High-Risk Relapsed B-ALL (Medicine) 8 Mar 2021 A study involving researchers from the Cancer Center at Children’s Hospital of Philadelphia (CHOP) has shown that blinatumomab, a bispecific T cell-engaging antibody, is less toxic than chemotherapy with similar or better…
Medicine Deep Immune Profiling Shows Significant Immune Activation in Children with MIS-C (Medicine) 6 Mar 2021 CHOP/Penn study shows T cell activation in children with MIS-C more similar to adults with severe COVID-19 Taking the first deep dive into how the immune system is behaving in…
Medicine Researchers Take Early Step Toward Leukemia Drug Therapy (Medicine) 17 Feb 2021 Focus on adult AML has revealed encouraging results A McMaster stem cell research team has made an important early step in developing a new class of therapeutics for patients with…
Medicine Moffitt Researchers Identify Why CAR T Therapy May Fail in Some Lymphoma Patients (Medicine) 2 Feb 2021 Chimeric antigen receptor T-cell therapy, or CAR T, has been a breakthrough in the treatment of blood cancers such as acute lymphoblastic leukemia and diffuse large B-cell lymphoma. Clinical studies…
Medicine When Hyperactive Proteins Trigger Illnesses (Medicine) 2 Feb 2021 Researchers find trigger for autoimmune diseases and cancer of the lymph node Autoimmune diseases, in which the body's own immune system attacks healthy tissue, can be life-threatening and can impact…
